性質(zhì)：Properties
本品在280℃真空升華，可溶于乙二醇二甲醚、二甘醇二甲醚和四氫呋喃，微溶于。在干燥的空氣中穩定，在潮濕的空氣中吸潮水解。本品是一種溫和的高選擇性還原劑，在0℃的醚或二甘醇中可還原酮、醛、和酰氯，不還原脂肪酸酯和腈，但可還原脂肪酸和酯環(huán)酸的苯酯。
This product sublimes at 280℃ under vacuum. It is soluble in dimethoxyethane, diglyme and THF, and slightly soluble in diethyl ether. It is stable in dry air but it can be hydrolyzed in moist air. This product is a mild high selective reducing agent, which can reduce ketones, aldehydes and acyl chloride in diethyl ether or diethylene glycol at 0℃. It can’t reduce aliphatic acid ester and nitrile, but can reduce phenyl esters of aliphatic acid and alicyclic acid.
用途 Usage
在醫藥、香料、農藥、染料以及其他精細有機合成中用作還原劑。廣泛用于甾體酮的還原。在抗艾滋病的原料藥阿扎那韋的生產(chǎn)中用作還原劑。
It is used as reducing agent in organic synthesis of pharmaceuticals, perfumes, pesticides, dyes and other fine chemicals. It was widely used in reducing steroid ketone. It is used as the reducing agent for synthesizing Azanavir, which is an anti-AIDS API.
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