Dexamethasone is a potent glucocorticoid with minimal mineralocorticoid activity. It exerts its effects by binding to intracellular glucocorticoid receptors, which then translocate to the nucleus and modulate gene expression. This leads to a reduction in the production of pro-inflammatory cytokines, chemokines, and other inflammatory mediators. Additionally, dexamethasone stabilizes lysosomal membranes, reduces capillary permeability, and inhibits the migration and proliferation of immune cells. These actions collectively result in significant anti-inflammatory and immunosuppressive effects.
Dexamethasone injection is used to treat a wide range of conditions, including:
The dosage of dexamethasone injection varies depending on the condition being treated:
Dexamethasone injection should be stored in a cool, dry place, protected from light and moisture. The storage temperature should be between 15°C and 30°C (59°F to 86°F) unless otherwise specified. Keep the container tightly closed to maintain stability and efficacy.
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